Category:
Active Pharmaceutical Ingredients
CAS NO:
1
Standard:
USP;BP,
Methotrexate is a folate antagonist primarily synthesized via catalytic condensation of cyanamide and glutamic acid derivatives. Its molecular formula is C20H22N8O5 (CAS: 59-05-2).
Strictly contraindicated in severe hepatic or renal impairment. Requires specialized PPE handling to prevent dermal absorption. Store under controlled temperature (<25°C) in a dry, light-resistant environment.