Category:
Active Pharmaceutical Ingredients
CAS NO:
1
Standard:
USP;BP,
Mitoxantrone Hydrochloride is a synthetic anthracenedione derivative used primarily in oncology. It functions as a DNA intercalating agent and topoisomerase II inhibitor. The compound features the molecular formula C22H28N4O6 with CAS No. 71590-80-2. Industrial synthesis typically involves controlled oxidation of precursors followed by salt formation.
Strictly contraindicated for patients with severe bone marrow suppression. Requires dark storage at 2-8°C to prevent photodegradation. Handling demands full PPE due to potent cytotoxicity and potential carcinogenic risks.