Obeticholic acid is a semi-synthetic bile acid analogue and acts as a farnesoid-X receptor (FXR) agonist. It is used for the treatment of primary biliary cholangitis. It is also under investigation for the treatment of other liver diseases,primary biliary cirrhosis, bile acid diarrhea and related disorders
Obeticholic Acid (CAS: 128569-47-7) is a synthetic bile acid derivative with molecular formula C24H34O5. It serves as a potent agonist for the farnesoid X receptor (FXR), primarily manufactured via chemical synthesis for pharmaceutical grade purity.
Contraindicated in patients with complete biliary obstruction. Requires strict storage below 25°C in dry conditions. Monitor liver enzymes closely during therapy to prevent hepatotoxicity risks.