Paroxetine hydrochloride CAS 78246-49-8 is an antidepressant that is an efficient serotonin reuptake inhibitor that can inhibit GRK2 activity with an IC50 value of 14 μM.
*The following content is generated by AI and is for reference only.
Overview
Paroxetine hydrochloride is a selective serotonin reuptake inhibitor (SSRI) synthesized via chiral resolution or asymmetric catalysis. Its molecular formula is C19H20ClNO3·HCl, with CAS No. 61869-08-7.
Application
- Pharmaceutical manufacturing for antidepressant formulations.
- Treatment of major depressive disorder and panic disorder.
- Research applications in neuroscience for serotonergic pathway studies.
Precautions
Strictly controlled due to CNS activity; requires storage below 25°C in dry conditions. Avoid exposure during handling to prevent inhalation risks.