Description:Pemigatinib is a selective FGFR inhibitor in development for the treatment of patients with cholangiocarcinoma.
Target:FGFR
Boiling point :697.6±55.0 °C
density :1.44±0.1 g/cm3
storage temp:Store at -20°C
solubility:DMSO:40.0(Max Conc. mg/mL);82.05(Max Conc. mM)
form :A crystalline solid
pka:11.56±0.40(Predicted)
Molecular Weight:487.499
Exact Mass:487.203125
LogP:0.66
Index of Refraction:1.620
Pemigatinib is a potent, selective FGFR inhibitor developed for oncology. It features a distinct pyrazolopyrimidine core structure with molecular formula C21H20FN5O and CAS number 1678487-94-3.
Strictly store below -20°C in desiccated conditions. Handle with PPE due to potential mutagenicity. Contraindicated in patients with severe hepatic impairment or active ocular disorders.