Sorafenib tosylate is a potent multikinase inhibitor, with IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.
*The following content is generated by AI and is for reference only.
Overview
Sorafenib Tosylate is the tosyl salt of Sorafenib, a multikinase inhibitor. CAS 284461-73-0 and formula C21H16F3N5O·C7H8O3S define its identity. Produced via controlled crystallization from organic solvents.
Application
- Pharmaceutical API for oncology drug formulation
- Targeted therapy for hepatocellular carcinoma (HCC)
- Treatment of advanced renal cell carcinoma (RCC)
Precautions
Store below 25°C in dry, dark conditions. Avoid direct contact due to potential toxicity. Contraindicated in pregnancy; strict occupational safety protocols required during handling.