Chemical Name:(5R,6S)-6-((R)-1-hydroxyethyl)-3-(((1R)-1-oxidotetrahydrothiophen-3-yl)thio)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
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Overview
Sulopenem is a novel oral carbapenem antibiotic developed to treat complicated intra-abdominal infections. Its core synthesis involves asymmetric catalysis to ensure stereochemical purity. The molecular formula is C15H24N4O4S with CAS No. 170963-85-0.
Application
- Treatment of community-acquired pneumonia in adult patients.
- Management of complicated urinary tract infections.
- Combination therapy for multidrug-resistant bacterial strains.
Precautions
Contraindicated in patients with known hypersensitivity to beta-lactams. Store under controlled room temperature away from moisture. Monitor renal function during prolonged administration to prevent toxicity.