Category:
Prophylactic Biological Products
CAS NO:
NA
Standard:
In-house Standards,
Tenofovir Alafenamide (TAF) is a prodrug of tenofovir designed for enhanced intracellular delivery. Its core synthesis involves phosphoramidate coupling to improve stability and reduce systemic exposure. Molecular formula: C24H31N6O7P; CAS No.: 1350783-64-6.
Contraindicated in severe renal impairment without dose adjustment. Requires storage below 30°C in dry conditions. Strict adherence to pharmacovigilance protocols regarding bone mineral density changes is mandatory during clinical use.