Category:
Other Excipients
TIANDIDA® (Amifostine Injection) is a cytoprotective agent primarily used to mitigate renal toxicity and xerostomia associated with platinum-based chemotherapy. The active pharmaceutical ingredient, Amifostine, functions as an organic thiophosphate prodrug converted by alkaline phosphatase into its active thiol metabolite, WR-1065. Its molecular formula is C8H18N2O3PS with CAS Registry Number 94357-96-1.
Strict clinical monitoring is required due to risks of hypotension and nausea/vomiting. Administration must occur under controlled medical settings with pre-hydration protocols. Store the injection at controlled room temperature between 20°C and 25°C, protecting from light and freezing conditions.