Appearance:
white to off-whitecrystalline powder
Molecular Weight:
285.31
Density:
1.21g/cm3
Boiling Point:
374.4 °C at 760 mmHg
Melting Point:
181-183℃
Flash Point:
180.3 °C
Storage Temperature:
Store in original container in a cool dark place.
Solubility:
Insoluble
Usage:
A nonsteroidal aromatase inhibitor structurally related to Fadrozole. Antineoplastic
*The following content is generated by AI and is for reference only.
Overview
Letrozole is a non-steroidal aromatase inhibitor used in pharmaceutical synthesis. Molecular Formula: C17H11N5; CAS No.: 112809-51-5. Core processes involve condensation reactions and crystallization for API grade purity.
Application
- Hormone-dependent breast cancer treatment (postmenopausal women).
- First-line therapy for advanced breast carcinoma.
- Off-label use in fertility protocols to induce ovulation.
Precautions
Contraindicated in pregnancy and premenopausal women. Store in cool, dry conditions away from light. Personnel must wear PPE to prevent inhalation or skin contact during handling.