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Overview
5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine serves as a critical synthetic intermediate for the API Abemaciclib. This compound is primarily produced via nucleophilic substitution reactions involving pyridine derivatives and ethylpiperazine. The molecular formula is C11H17N3, with CAS No. 1860965-45-4.
Application
- Pharmaceutical manufacturing: Key building block for CDK4/6 inhibitor synthesis.
- Research & Development: Used in oncology drug discovery pipelines.
- Custom synthesis: Supplier for specialized medicinal chemistry projects.
Precautions
Store in sealed containers under inert atmosphere at controlled temperatures. Handle with appropriate PPE to avoid skin contact or inhalation, ensuring compliance with GMP standards during clinical supply chains.