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Overview
Apremilast is a selective PDE4 inhibitor used in dermatology and rheumatology. Its molecular formula is C21H26N4O5 (CAS: 490455-76-0), synthesized via multi-step organic coupling.
Application
- Treatment of moderate-to-severe plaque psoriasis.
- Management of active pustular psoriasis.
- Therapy for psoriatic arthritis.
Precautions
Contraindicated in severe hepatic impairment. Monitor for depression and weight loss. Store at controlled room temperature (20-25°C) in dry conditions.