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Overview
Ferumoxytol is an ultrafine superparamagnetic iron oxide nanoparticle used primarily as a contrast agent and iron replacement therapy. Its core synthesis involves coating magnetic cores with carboxymethyldextran to ensure stability. The compound is identified by the molecular formula C12H20FeO10·nH2O (CAS: 89553-74-2).
Application
- Diagnostics: MRI contrast enhancement for liver lesion characterization.
- Therapeutics: Treatment of iron deficiency anemia in chronic kidney disease patients.
- Research: Cellular labeling and tracking in preclinical studies.
Precautions
Strictly monitor for hypersensitivity reactions, particularly anaphylaxis, during administration. Store at controlled room temperature between 20°C and 25°C. Do not freeze or shake the solution to prevent particle aggregation.