API
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Overview
Osimertinib mesylate is the mesylate salt form of osimertinib, a third-generation Tyrosine kinase inhibitor (TKI). It features a specific chemical structure with CAS 1720985-52-1 and molecular formula C26H28N4O2·CH4O3S. Manufactured via high-purity crystallization processes to ensure pharmaceutical grade quality.
Application
- Oncology Manufacturing: Primary API for treating EGFR T790M mutation-positive non-small cell lung cancer (NSCLC).
- Pharmaceutical Formulation: Used in solid dosage forms including tablets for oral administration.
- Research & Development: Sourced as reference standard for clinical trials and bioequivalence studies.
Precautions
Strictly store under controlled temperature (2°C–8°C) away from moisture. Handling requires PPE due to potential cytotoxicity; avoid inhalation or skin contact during industrial processing.