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Overview
Brinzolamide is a topical carbonic anhydrase inhibitor used to lower intraocular pressure. Its molecular formula is C9H18N2O4S3 with CAS 120635-85-8. The core synthesis involves sulfonamide coupling reactions.
Application
- Ophthalmology: Treatment of glaucoma and ocular hypertension.
- Pharmaceutical Manufacturing: API production for branded and generic eye drops.
- Research: In vitro studies on retinal fluid dynamics.
Precautions
Contraindicated in patients with severe renal impairment or sulfa allergy. Store in a dry environment at controlled room temperature (20-25°C) away from direct light.