Appearance:
Off-White Cyrstalline Solid
Molecular Weight:
389.40
Density:
1.51 g/cm3
Boiling Point:
679.1oC at 760 mmHg
Melting Point:
298-300°C
Flash Point:
364.5oC
Refractive index:
1.705
Solubility:
In water, 220 mg/L at 25 deg C /Estimated/
Usage:
Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor
*The following content is generated by AI and is for reference only.
Overview
Tadalafil is a potent PDE5 inhibitor used in pharmaceutical manufacturing. Its core synthesis involves complex organic coupling reactions. Molecular formula: C22H19N3O4; CAS No.: 171596-29-5.
Application
- Erectile Dysfunction: Long-acting treatment for adult male patients.
- BPH Management: Alleviates urinary symptoms associated with benign prostatic hyperplasia.
- Pulmonary Hypertension: Used off-label to reduce pulmonary vascular resistance.
Precautions
Strictly contraindicated with nitrates due to severe hypotension risks. Store in cool, dry conditions below 25°C away from direct sunlight. Handle active ingredients with appropriate PPE to prevent inhalation or skin contact.