*The following content is generated by AI and is for reference only.
Overview
Daprodustat intermediate (CAS 35824-91-0) is a key synthetic precursor for hypoxia-inducible factor prolyl hydroxylase inhibitors. Its molecular formula is C14H16N2O3. The core process involves selective functionalization of the heterocyclic scaffold to ensure high purity for pharmaceutical synthesis.
Application
- Anemia treatment in chronic kidney disease patients.
- Development of oral HIF-PH inhibitors for iron metabolism disorders.
- Intermediate supply for API manufacturing in large-scale chemical production.
Precautions
Storage requires sealed containers at 2-8°C away from moisture. Handling demands PPE due to potential irritant properties. Clinical use is restricted to regulated indications under physician supervision.