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Overview
Fludarabin Phosphate is a synthetic nucleotide analog used in oncology. Synthesized via phosphorylation of fludarabine, its molecular formula is C10H14FN5O4P and CAS No. 75607-58-2.
Application
- Treatment of chronic lymphocytic leukemia (CLL).
- B-cell malignancies requiring purine analog therapy.
- Chemotherapy regimens for refractory lymphomas.
Precautions
Strictly contraindicated in severe renal impairment. Requires cold chain storage at -20°C. Personnel must use PPE to prevent dermal exposure during compounding.