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Overview
Gadodiamide hydrate is a gadolinium-based contrast agent (GBCA) used primarily in magnetic resonance imaging. It is synthesized via chelation of gadolinium ions with diethylenetriaminepentaacetic acid derivatives. The compound features the molecular formula C19H28GdN3O10·xH2O and carries CAS number 146574-52-7.
Application
- MRI diagnostics for neurological disorders including tumors and multiple sclerosis.
- Vascular imaging to visualize blood flow abnormalities and aneurysms.
- Oncology screening for tumor detection and treatment response monitoring.
Precautions
Contraindicated in patients with severe renal impairment due to nephrogenic systemic fibrosis risk. Strict adherence to dosage limits is required. Store in a cool, dry place away from direct sunlight to maintain chemical stability.