Name:
Ledipasvir (Related Reference)
Molecular Formula:
C49H54F2N8O6
CAS Registry Number:
1256388-51-8
Synonyms:
GS 588
Chemical Properties
Molecular Weight:
889.00
Density:
1.42±0.1 g/cm3 (20 oC 760 Torr)
Melting Point:
(5.9E-5 g/L) (25 oC)
*The following content is generated by AI and is for reference only.
Overview
Ledipasvir is a potent direct-acting antiviral agent targeting the HCV NS5A protein. Synthesized via advanced chiral catalysis, its molecular formula is C27H18F3N5O6 (CAS: 1043191-79-2).
Application
- Hepatology: First-line component in fixed-dose combinations for treating chronic Hepatitis C.
- Pharmaceutical Manufacturing: Active Pharmaceutical Ingredient (API) for generic antiviral tablet production.
Precautions
Strictly contraindicated with amiodarone due to bradycardia risks. Store API at controlled room temperature (20-25°C) in moisture-proof containers to maintain stability.