Appearance:
White Crystalline Solid
Molecular Weight:
628.80
Density:
1.163 g/cm3
Boiling Point:
924.1 °C at 760 mmHg
Melting Point:
124-127°C
Flash Point:
512.7 °C
Refractive index:
1.577
Usage:
A selective HIV protease inhibitor. An analogue of Ritonavir
*The following content is generated by AI and is for reference only.
Overview
Lopinavir is a potent protease inhibitor utilized in antiretroviral therapy. Synthesized via advanced organic coupling, its molecular formula is C57H74N10O8 with CAS No. 192725-17-0.
Application
- Virology: Combined with ritonavir for treating HIV-1 infection.
- Pharmaceutical Manufacturing: Bulk API production for fixed-dose combination tablets.
- Clinical Research: Studied for antiviral efficacy against emerging coronaviruses.
Precautions
Strictly contraindicated with specific CYP3A substrates. Store below 25°C in dry conditions. Requires professional medical supervision due to potential hepatotoxicity and drug-drug interactions.