Appearance:
white crystalline powder
Molecular Weight:
377.86186
Density:
1.47 g/cm3
Boiling Point:
558.1 °C at 760 mmHg
Melting Point:
274-2760C
Flash Point:
291.4 °C
Storage Temperature:
2-8°C
Solubility:
H2O: 50 mg/mL, clear, colorless
Biological Activity:
Opioid antagonist.
Usage:
Nonselective opioid receptor antagonist; congener of naloxone
*The following content is generated by AI and is for reference only.
Overview
Naltrexone HCl is a potent opioid antagonist synthesized via acetylation of naltrexol. Its molecular formula is C20H23NO4·HCl (CAS: 13856-09-2).
Application
- Pharmaceuticals: Management of opioid and alcohol dependence.
- Research: Receptor binding studies in neurobiology.
- Veterinary Medicine: Off-label treatment for compulsive behaviors.
Precautions
Requires verified abstinence from opioids prior to administration to prevent acute withdrawal. Store in sealed containers below 25°C away from moisture and light.