Molecular Weight:
416.6365
Density:
1.121 g/cm3
Boiling Point:
564.8 °C at 760 mmHg
Flash Point:
238.4 °C
Refractive index:
1.609
Solubility:
In water, 1.2X10-3 mg/L at 25 deg C (est)
*The following content is generated by AI and is for reference only.
Overview
Paricalcitol (CAS 126934-68-7) is a synthetic vitamin D analog with molecular formula C27H44O3. It is produced via semi-synthesis from 7-dehydrocholesterol derivatives, featuring a selective activation of the vitamin D receptor.
Application
- Treatment of secondary hyperparathyroidism in chronic kidney disease patients on dialysis.
- Management of hypocalcemia and parathyroid hormone elevation in end-stage renal failure.
- Research applications for bone metabolism regulation studies.
Precautions
Contraindicated in patients with hypercalcemia or vitamin D toxicity. Store in a cool, dry place below 25°C protected from light. Strict adherence to dosage protocols is required to prevent hypercalcemic complications.