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Overview
Erlotinib Hydrochloride is a pharmaceutical grade API used as a tyrosine kinase inhibitor. It features a quinazoline core synthesized via condensation reactions. The compound has the molecular formula C22H23ClN4O·HCl and CAS number 183319-69-9.
Application
- Non-small cell lung cancer (NSCLC) therapy for EGFR mutation-positive patients.
- Pancreatic cancer treatment in combination with gemcitabine.
- R&D of oncology drugs targeting specific epidermal growth factor receptors.
Precautions
Requires prescription only; monitor for interstitial lung disease and skin toxicity. Store at 2°C to 8°C in airtight containers protected from light and moisture.