Evocalcet is an orally available calcium receptor (CaR) modulator, with potential calcimimetic activity. Upon administration, evocalcet allosterically binds to and inhibits the activity of CaR, thereby suppressing the production of serum parathyroid hormone (PTH) and prevents the PTH-mediated efflux of calcium from bone and normalizes calcium levels.
Evolocalcet is a pharmaceutical grade active pharmaceutical ingredient (API) utilized in endocrine therapy. Its molecular formula is C15H17ClN2O4 and CAS number is 96802-43-4. The compound is synthesized via advanced organic coupling processes ensuring high purity.
Strictly monitor serum calcium during therapy to prevent hypercalcemia. Store in a cool, dry place below 25°C away from direct sunlight. Handle with appropriate PPE due to potential irritant properties.