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Overview
Saxagliptin is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor used in pharmaceutical synthesis. Its core manufacturing process involves asymmetric catalysis and chiral resolution to ensure high enantiomeric purity. Molecular formula: C18H25N5O3; CAS No.: 202375-16-8.
Application
- Pharmaceutical Manufacturing: Bulk active ingredient for Type 2 diabetes treatments.
- API Production: Formulation into fixed-dose combination tablets with metformin.
- Research & Development: Clinical trials for metabolic syndrome management.
Precautions
Strictly avoid use in patients with severe hepatic impairment or history of hypersensitivity. Store API in cool, dry conditions below 25°C under inert atmosphere to prevent hydrolysis and degradation.