API
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Overview
Abiraterone acetate is a potent oral androgen biosynthesis inhibitor. It features the molecular formula C24H35NO3 and CAS number 154229-18-2. Core manufacturing involves complex organic synthesis with high-purity crystallization.
Application
- Oncology: Treatment of metastatic castration-resistant prostate cancer (mCRPC).
- Pharmaceutical Manufacturing: API production for combination therapies with prednisone.
Precautions
Contraindicated in pregnancy due to fetal harm. Requires storage below 25°C in dry, light-protected environments. Personnel must use appropriate PPE to prevent inhalation or dermal exposure during handling.