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Overview
Dabigatran etexilate mesylate is a prodrug of dabigatran, serving as a potent direct thrombin inhibitor. Synthesized via esterification and salt formation, its molecular formula is C20H29N5O4·CH4O3S with CAS No. 786991-05-3.
Application
- Pharmaceutical manufacturing for oral anticoagulant tablets.
- Treatment of stroke prevention in non-valvular atrial fibrillation.
- Management of deep vein thrombosis and pulmonary embolism.
Precautions
Contraindicated in patients with active bleeding or severe renal impairment. Store in cool, dry conditions below 25°C away from light to maintain stability.