*The following content is generated by AI and is for reference only.
Overview
Etelcalcetide HCl is a synthetic, injectable calcimimetic agent used to manage secondary hyperparathyroidism in patients with chronic kidney disease. Its core process involves solid-phase peptide synthesis followed by hydrochloride salt formation. The compound features the molecular formula C64H98N18O14S and CAS number 1025872-37-4.
Application
- Pharmaceutical Manufacturing: Bulk production of dialysis-grade injectables for renal care.
- Clinical Treatment: Intravenous administration during hemodialysis sessions to lower parathyroid hormone levels.
Precautions
Strictly contraindicated for patients with hypocalcemia. Requires storage in controlled temperature environments (2°C–8°C) to maintain peptide stability. Handling mandates PPE due to potential irritant properties of the active pharmaceutical ingredient.