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Overview
Palbociclib is a selective CDK4/6 inhibitor used in oncology manufacturing. The core synthesis involves complex organic coupling reactions. Molecular formula: C27H35ClN4O3; CAS No.: 982271-28-3.
Application
- Pharmaceutical API production for metastatic breast cancer therapies.
- R&D supply for clinical trials targeting HR+/HER2- cancers.
- Contract manufacturing for combination regimens with endocrine therapy.
Precautions
Strictly store below 25°C in dry, inert atmosphere. Handle as hazardous substance; avoid inhalation and skin contact. Contraindicated in severe hepatic impairment without dose adjustment protocols.