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Overview
Ruxolitinib phosphate is a JAK1/JAK2 inhibitor used in oncology. Molecular formula: C20H24N6O8P; CAS No: 957320-50-6. Synthesized via phosphoric acid esterification of ruxolitinib.
Application
- Hematologic malignancies treatment for myelofibrosis.
- Management of polycythemia vera patients.
- Research applications for inflammatory pathway studies.
Precautions
Contraindicated in severe hepatic impairment. Store at controlled room temperature (20-25°C). Handle with PPE to avoid inhalation or skin contact during manufacturing.