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Overview
Sitagliptin phosphate monohydrate is a high-purity API intermediate for DPP-4 inhibitors. Synthesized via chiral resolution, its molecular formula is C16H18F3N5O8P and CAS No. is 559094-72-3.
Application
- Type 2 diabetes mellitus management as active pharmaceutical ingredient.
- Custom synthesis of fixed-dose combination tablets with metformin.
- Research-grade reagent for metabolic pathway studies.
Precautions
Store in sealed containers at 2-8°C to prevent hydrolysis. Avoid inhalation; use PPE during handling. Not indicated for type 1 diabetes or diabetic ketoacidosis.