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Overview
Flurbiprofen (CAS: 51047-29-5) is a non-steroidal anti-inflammatory drug (NSAID) synthesized via Friedel-Crafts acylation. Its molecular formula is C15H14O2, serving as a potent cyclooxygenase inhibitor.
Application
- Ophthalmology: Topical treatment for ocular inflammation during cataract surgery.
- Rheumatology: Management of pain and stiffness in osteoarthritis and rheumatoid arthritis.
- Pharmaceutical Manufacturing: Bulk active pharmaceutical ingredient (API) for tablet and ointment production.
Precautions
Contraindicated in patients with hypersensitivity to aspirin or NSAIDs. Store in cool, dry conditions below 25°C. Handle with PPE to prevent respiratory irritation and skin contact.