*The following content is generated by AI and is for reference only.
Overview
Flurbiprofen Axetil is a lipophilic prodrug of the NSAID flurbiprofen, designed to enhance aqueous solubility and bioavailability. Synthesized via esterification, its molecular formula is C16H15FO4 (CAS 59870-20-1). The ester linkage hydrolyzes in vivo to release the active parent drug.
Application
- Ophthalmology: Treatment of intraoperative miosis and inflammation during cataract surgery.
- Pharmaceutical Manufacturing: Intermediate for preparing ophthalmic solutions and eye drops.
- Research: Tool compound for studying prostaglandin inhibition mechanisms.
Precautions
Strictly controlled for human use only; avoid direct contact with skin or eyes. Store in a cool, dry place below 25°C protected from light to prevent hydrolysis. Do not mix with alkaline solutions.