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Overview
Letermovir is a non-nucleoside inhibitor of the human cytomegalovirus (CMV) terminase complex, synthesized via advanced organic coupling. Its molecular formula is C28H36N4O5 with CAS No. 1039074-38-0.
Application
- Prevention of CMV infection in allogeneic hematopoietic stem cell transplant recipients.
- Antiviral prophylaxis in high-risk clinical populations during post-transplant recovery.
- Industrial-scale API production for pharmaceutical formulation supply chains.
Precautions
Contraindicated with cyclosporine due to severe drug-drug interactions; requires strict temperature control below 25°C and protection from light during storage.