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Overview
Mirogabalin is a novel gabapentinoid analgesic developed for neuropathic pain management. Its core synthesis involves chiral resolution and selective alkylation steps. The molecular formula is C15H22N2O with CAS number 189643-07-4.
Application
- Pharmaceutical Manufacturing: Active pharmaceutical ingredient (API) production for chronic neuropathic pain formulations.
- Clinical Research: Investigational compound in Phase III trials for diabetic peripheral neuropathy and lumbar spinal stenosis.
- Distribution: Bulk supply to licensed generic drug manufacturers under strict regulatory frameworks.
Precautions
Strictly contraindicated for patients with severe renal impairment without dose adjustment. Storage requires controlled temperature between 2°C and 8°C, protected from light and moisture to maintain stability.