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Overview
Olmesartan medoxomil is a third-generation angiotensin II receptor blocker (ARB) used primarily for hypertension. Key chemical parameters include the molecular formula C29H30N6O6 and CAS number 144689-07-2. The core synthesis involves esterification of olmesartan with chloromethyl 2-methylpropanoate.
Application
- Pharmaceutical Manufacturing: Active Pharmaceutical Ingredient (API) for antihypertensive tablets.
- Cardiovascular Therapy: Treatment of essential hypertension in adult patients.
- Research & Development: Reference standard for bioequivalence studies.
Precautions
Contraindicated in pregnancy due to fetal toxicity risks. Store API in a cool, dry place below 25°C protected from light. Personnel must use appropriate PPE to avoid inhalation or skin contact during handling.