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Overview
PeraMpanel (Perampanel) is a non-competitive AMPA receptor antagonist used in epilepsy management. Synthesized via phthalimide condensation, its molecular formula is C19H15N3O2 and CAS number is 687024-59-3.
Application
- Neurology: Adjunctive treatment for partial-onset seizures with or without secondary generalization.
- Research: Investigational use in studying excitotoxicity mechanisms and neuroprotection.
- Pharmaceuticals: Active pharmaceutical ingredient (API) formulation for oral tablets.
Precautions
Contraindicated in patients with known hypersensitivity. Requires strict storage below 25°C in dry conditions. Clinical monitoring is essential due to potential neuropsychiatric adverse effects.